“PARALYZED STOMACHS!” on a GLP-1?! [glp 1 weight loss medications]

“PARALYZED STOMACHS!” on a GLP-1?! [glp 1 weight loss medications]

| 1h 28m 28s | Video has closed captioning.

The headlines about these drugs could give content every day. Here is the next big one. “PARALYZED STOMACHS!” What they are saying is that a few people developed permanent gastroparesis from these new medicines (GLP-1 agonists eg wegovy or ozempic). These drugs are known to slow down gastric emptying (how quickly your stomach digests). However, this effect usually decreases over time and what you’re left with is the satiety from the effect on the brain and not the nausea and bloating from your stomach being full. This report is saying one or two people said they still had this feeling after stopping. We have no other history. It’s possible these individuals had an underlying condition like type 2 diabetes where they already had gastroparesis. Hard to tell. What I will say is that it’s not been seen in the trials and we haven’t encountered this in our 10s of thousands of patients at Sequence. If it does occur it would have to be extremely rare.